Study reveals that dandelion root can induce cancer cell suicide in over 90% of colon cancer cells within just 48 hours!
Dandelion root extract (DRE) appears to trigger apoptosis (programmed cell death) in aggressive cancer cells lines such colon cancer, melanoma and leukemia with minimal to no effect on healthy cells.
DRE targets the altered metabolic pathways within cancer cells. Research shows DRE disrupts the mitochondrial membrane potential and increases Reactive Oxygen Species (ROS) levels in cancer cells’ mitochondria.
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Studies indicate that DRE can affect specific signaling pathways involved in cancer cell proliferation and survival. For instance, it may activate the extrinsic pathway of apoptoses, potentially involving caspase-8 activation.
In breast cancer, DRE may affect the P13K/AKT signaling pathways involved by inhibiting the expression of choline kinase α (CHKA).
DRE can also influence the expression of genes associated with cell death and survival. Studies show that DRE treatment led to the upregulation of pro-apoptotic genes and downregulation of anti-apoptotic genes in certain cancer cell lines.
